Antibody Production and Purification
ABclonal Technology ASym DiMethyl-Histone H3-R8
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A H2B H3 and H4) The chromatin fiber is further compacted through the interaction of a linker histone H1 with the DNA between the nucleosomes to form higher order chromatin structures This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family Transcripts from this gene lack polyA tails instead they contain a palindromic termination element This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21 3
Invivogen POLY(I:C) (HMW) VACCIGRADE
Poly(I:C) is a synthetic double-stranded RNA, that can activate the immune response through two distinct PRRs. Endosomal poly(I:C) activates TLR3 while cytosolic poly(I:C) activates RIG-I/MDA-5. Triggering the TLR3 pathway induces IL-12 and type I IFNs production, while stimulation of MDA-5 enhances the production of type I IFNs. Poly(I:C) promotes Th1 biased immunity through its induction of IL-12 and type I IFNs.
Invivogen ALUMINUM HYDROXIDE GEL 250ML
Alhydrogel adjuvant 2% is an aluminium hydroxide (referred to as alum) wet gel suspension. Alum acts primarily through the formation of a depot at the injection site, enabling enhanced antigen availability, activation of antigen presenting cells (APCs) and uptake by immune cells. It can also activate innate immunity pathways triggered by pattern recognition receptors (PRRs). The NLR pathway has been recently described as an important mechanism in alum adjuvancy. Alum has been shown to activate the NLRP3 inflammasome although its role in alum-induced antibody response is controversial. 21645-51-2.
ABclonal Technology Sym DiMethyl-Histone H3-R8
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes This structure consists of approximately 146 bp of DNA wrapped around a nucleosome an octamer composed of pairs of each of the four core histones (H2A H2B H3 and H4) The chromatin fiber is further compacted through the interaction of a linker histone H1 with the DNA between the nucleosomes to form higher order chromatin structures This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family Transcripts from this gene lack polyA tails instead they contain a palindromic termination element This gene is found in the large histone gene cluster on chromosome 6p22-p21 3
Sigma Aldrich Fine Chemicals Biosciences HEMOCYANIN FROM MOLLUSK 100MG
NC2942191 HEMOCYANIN FROM MOLLUSK 100MG